By Frank L. Iber M.D., W. Anthony Riley M.D., Patricia J. Murray B.A. (auth.)
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The potential drawbacks to participating in clinical trials are also experienced at the organizational and staff levels. While the suboptimally utilized facility may be used for research purposes, the use of this resource for research tasks requires considerable effort, particularly if the staff is not compensated for the real or perceived DECIDING TO ENTER THE RESEARCH FIELD 25 increase in activity. The authors frequently have observed very willing, enthusiastic investigators whose efforts to conduct a clinical trial were undermined by a reluctant, poorly oriented, and poorly supervised staff.
Initially they were delivered, but with a great deal of frustration that evolved into hostility. The investigator did not fully appreciate, however, that while he had been an enthusiastic general health provider while the patient was in the study, his attitude had subsequently shifted to one of lack of interest after the study was completed. The nature of the change in the relationship from a research care to a private practice setting and its significance had not been shared with the patient. " Participation in clinical research will impose burdens on the investigator's staff, colleagues, and facility.
We will adjust this sufficiently to obtain control, and then plan to return him to your care. The initial ECG, chemistries, urine examination, and ophthalmological consultations that we obtained are enclosed for your records. If we can supply further information about this study please call me at 123-4567. D. FIGURE 2. Letter to a physician providing regular hypertensive treatment to a patient who is about to be enrolled in a one-year, placebo-controlled trial. his physician that is seldom clearly articulated and almost never written.
Conducting Clinical Trials by Frank L. Iber M.D., W. Anthony Riley M.D., Patricia J. Murray B.A. (auth.)