Download PDF by Shira Knafo, César Venero: Cognitive Enhancement: Pharmacologic, Environmental and

By Shira Knafo, César Venero

ISBN-10: 0124170420

ISBN-13: 9780124170421

Cognitive Enhancement: Pharmacologic, Environmental and Genetic Factors addresses the space that exists in examine at the subject, amassing multidisciplinary wisdom and instruments that aid the reader comprehend the fundamentals of cognitive enhancement. It additionally offers assistance in designing techniques and pharmacological ways to extra using novel cognitive enhancers, a box that gives power profit to a number of populations, together with people with neurologic and psychiatric issues, gentle aging-related cognitive impairment, and people who are looking to increase highbrow functionality.

The textual content builds on our wisdom of the molecular/cellular foundation of cognitive functionality, providing the technological advancements which can quickly increase cognition. Separate sections disguise enhancement medicinal drugs, environmental stipulations, and genetic elements when it comes to either human and animal reports, together with either healthy/young and aging/diseased participants.

  • Provides a multidisciplinary wisdom, allowing a different figuring out of cognitive enhancement
  • Offers insurance of the pharmacologic, environmental, and genetic elements proper to the topic
  • Discusses cognitive enhancement from the point of view of either fit and diseased or getting older populations
  • Topics are mentioned when it comes to either human and animal studies

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Extra resources for Cognitive Enhancement: Pharmacologic, Environmental and Genetic Factors

Sample text

Brain-derived neurotrophic factor/TrkB signaling in memory processes. J. Pharmacol. Sci. 91, 267–270. , 2011. Protein kinase C promotes N-methyl-d-aspartate (NMDA) receptor trafficking by indirectly triggering calcium/ calmodulin-dependent protein kinase II (CaMKII) autophosphorylation. J. Biol. Chem. 286, 25187–25200. , 2011. ApoE is required for maintenance of the dentate gyrus neural progenitor pool. Development 138, 4351–4362. , 2012. Activation of TrkB by 7,8-dihydroxyflavone prevents fear memory defects and facilitates amygdalar synaptic plasticity in aging.

30, 572–580. , 2013. Stress and excitatory synapses: from health to disease. Neuroscience 248, 626–636. , 2005. The Rac1GEF Tiam1 couples the NMDA receptor to the activity-dependent development of dendritic arbors and spines. Neuron 45, 525–538. , 2007. The Rac1 guanine nucleotide exchange factor Tiam1 mediates EphB receptor-dependent dendritic spine development. Proc. Natl. Acad. Sci. A. 104, 7265–7270. , 2011. Control of synapse development and plasticity by Rho GTPase regulatory proteins. Prog.

2005. Rho GTPases, dendritic structure, and mental retardation. J. Neurobiol. 64, 58–74. , 2007. Increased response to morphine in mice lacking protein kinase C epsilon. Genes Brain Behav. 6, 329–338. , 1999. 4-methylcatechol increases brain-derived neurotrophic factor content and mRNA expression in cultured brain cells and in rat brain in vivo. J. Pharmacol. Exp. Ther. 291, 1276–1283. , 2005. Protein kinase C-epsilon regulates the apoptosis and survival of glioma cells. Cancer Res. 65, 7301–7309.

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Cognitive Enhancement: Pharmacologic, Environmental and Genetic Factors by Shira Knafo, César Venero


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