Clinical Research Methods for Surgeons - download pdf or read online

By Eugene H. Blackstone MD (auth.), David F. Penson MD, MPH, John T. Wei MD, MS (eds.)

ISBN-10: 1588293262

ISBN-13: 9781588293268

ISBN-10: 1597452300

ISBN-13: 9781597452304

Clinical examine tools for Surgeons is a entire advisor for the surgical scientist, and serves as either a severe evaluation of current literature and a reference consultant for medical examine methodologies as they practice to surgical procedure. The textual content addresses the medical learn questions dealing with twenty first century surgeons, and offers transparent path on tips to include refined learn recommendations into perform. as well as the surgical generalist, this sensible quantity is particularly orientated to surgeons who deal with precise ailments, but haven't any unmarried source to facilitate medical study in those particular areas.
This accomplished and easy-to-use consultant encompasses the total strategy of scientific research layout, software, and evaluation. half One is geared toward the younger doctor approximately to have interaction in new experiences, and offers a basic review of the infrastructure of medical examine. elements and 3 are geared in the direction of skilled investigators drawn to pursuing scientific learn and surgeons reviewing the literature for useful software. half specializes in research layout and comparable statistical matters, whereas half 3 is worried with measuring and assessing the result of medical reviews. half 4 offers themes of curiosity to the lively investigator, resembling caliber of care and cost-effectiveness analyses. scientific learn equipment for Surgeons is suitable to either starting investigators and demonstrated researchers, and addresses the original issues of surgical illnesses and recognizes that they require exact ways to accommodate medical questions.

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Preparing, maintaining, and disseminating systematic reviews of the effects of health care. JAMA 1995;274:1935–1938. 23. Chalmers I, Dickersin K, Chalmers TC. Getting to grips with Archie Cochrane’s agenda. Br Med J 1992;305:786–788. 24. Berry DA, Stangl DK. Meta-analysis in medicine and health policy. Biostatistics. New York: Marcel Dekker, 2000. 25. Fleming TR, DeMets DL. Surrogate end points in clinical trials: are we being misled? Ann Intern Med 1996;125:605–613. 26. Vineis P, McMichael AJ.

Title The title of a research proposal should reflect the question being addressed. It should indicate the (1) topic, (2) target population (including control group), (3) analytic approach, (4) end point, and (5) clinical importance. 2. Contributors Name the principal investigator (guarantor) and contributors. The role, responsibilities, and expectation of each should be agreed upon. As a minimum, contributors include colleagues, statisticians, data managers, and experts with respect to end points of the proposed research.

Identify limitations and anticipated problems. These can be identified by a brief but serious investigation of the state of all the considerations above. If any appear insurmountable or present fatal flaws that preclude later publication, the study should be abandoned before it is started. 10. Institutional Review Board Any proposal that does not use existing data already approved for use in research by an Institutional Review Board requires study-specific Institutional Review Board approval before any research is started.

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Clinical Research Methods for Surgeons by Eugene H. Blackstone MD (auth.), David F. Penson MD, MPH, John T. Wei MD, MS (eds.)


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