By Manjula K. Gupta PhD (auth.), Tommaso Falcone, William W. Hurd (eds.)
Clinical Reproductive medication and Surgery bargains a succinct evaluation of either the clinical and surgical administration of reproductive issues, in addition to assurance of linked imaging modalities. The e-book comprises chapters on significant reproductive endocrinology and infertility matters reminiscent of polycystic ovary syndrome and amenorrhea, administration of endometriosis and fibroids (including interventional radiology), imaging modalities reminiscent of ultrasonography and sonohysterography, maintenance of fertility, and recurrent being pregnant loss. citizens, fellows, and practitioners attracted to reproductive endocrinology and infertility will locate this concentrated and functional textual content invaluable.
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Additional info for Clinical Reproductive Medicine and Surgery: A Practical Guide
24. Kim HP, Lee JY, Jeong JK, Bae SW, Lee HK, Jo I. Nongenomic stimulation of nitric oxide release by estrogen is mediated by estrogen receptor alpha localized in caveolae. Biochem Biophys Res Commun. 1999;263(1):257–62. 25. Kannel WB, Hjortland MC, McNamara PM, Gordon T. Menopause and risk of cardiovascular disease: the Framingham study. Ann Intern Med. 1976;85(4):447–52. 26. Hu FB, Grodstein F, Hennekens CH, Colditz GA, Johnson M, Manson JE, et al. Age at natural menopause and risk of cardiovascular disease.
Progesterone Receptor Structure and Function Like ER, there are two major forms of PR: PR-A and PR-B receptors, which are derived from the same gene. PR-A and PR-B are identical except that PR-B contains an additional 164 amino acids sequence at the N-terminal end, which is referred to as the B-upstream segment (BUS) (Fig. 8). PR-A has a molecular weight of 94 kDa and contains 768 amino acids and PR-B is 114 kDa with 933 amino acids. The two forms derive from two distinct estrogen-regulated promoters .
If implantation occurs, it downregulates progesterone-induced genes and results in decidual necrosis and detachment of the conception products [181, 195]. Androgen Receptor Structure and Function The androgen receptor gene was cloned in 1988 and was localized on human X chromosome between the centromere and q13 . Like PR, AR also exists in two forms: a full-length B form and a shorter A form (molecular weights ~110 and 87 kDa); both are encoded by the single gene . The 87 kDa isoform (AR-A) contains the intact C terminus but lacks 188 amino acid residues in the N terminus of the 110 kDa isoform (AR-B) (Fig.
Clinical Reproductive Medicine and Surgery: A Practical Guide by Manjula K. Gupta PhD (auth.), Tommaso Falcone, William W. Hurd (eds.)