Clinical Neurology by Michael Aminoff, David Greenberg, Roger Simon PDF

By Michael Aminoff, David Greenberg, Roger Simon

ISBN-10: 0071423605

ISBN-13: 9780071423601

Famous for a practice-oriented method of neurology in line with the patient�s providing signs or symptoms. This uniquely readable and concise ebook presents a powerful beginning in easy neuroscience linking it to present ways within the analysis and remedy of neurologic problems. good points new suitable websites and a thesaurus in addition to broad use of charts and tables.

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B. LABORATORY FINDINGS CSF analysis is the most important laboratory test. CSF pressure is normal or increased, and a lymphocytic or monocytic pleocytosis is present, with cell counts usually less than 1000/mL. ) A polymorphonuclear pleocytosis can occur early in viral meningitis, while red blood cells may be seen with herpes simplex encephalitis. Protein is normal or slightly increased (usually 80–200 mg/dL). Glucose is usually normal, but may be decreased in mumps, herpes zoster, or herpes simplex encephalitis.

Clinical Findings A. SYMPTOMS AND SIGNS The clinical syndrome may include headache, stiff neck, vomiting, behavioral disorders, memory loss, anosmia, aphasia, hemiparesis, and focal or generalized seizures. Active herpes labialis is seen occasionally, but does not reliably implicate HSV as the cause of encephalitis. HSV encephalitis is usually rapidly progressive over several days and may result in coma or death. The most common sequelae in patients who survive are memory and behavior disturbances, reflecting the predilection of HSV for limbic structures.

Neurologic involvement becomes apparent weeks after infection. In addition to acute confusional states, cerebral malaria can produce seizures and, rarely, focal neurologic abnormalities. The diagnosis is made by finding plasmodia in red blood cells of peripheral blood smears. The CSF may show increased pressure, xanthochromia, mononuclear pleocytosis, or mildly elevated protein. Prophylaxis Malaria prophylaxis is recommended for travelers to areas where the disease is endemic and consists of chloroquine phosphate, 500 mg orally weekly, beginning 1–2 weeks before travel and continuing until 4 weeks after returning.

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Clinical Neurology by Michael Aminoff, David Greenberg, Roger Simon


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