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And French, A. S. (1994). Intracellular characterization of identified sensory cells in a new spider mechanoreceptor preparation. J. Neurophysiol. 71, 1422–1427. , and Tavernarakis, N. (2004). Genetic models of mechanotransduction: The nematode Caenorhabditis elegans. Physiol. Rev. 84, 1097–1153. , and Ku¨ppers, J. (1980). Epithelial physiology of insect sensilla. In ‘‘Insect Biology in the Future’’ (M. Locke and D. ), pp. 735–763. Academic Press, New York. Torkkeli, P. , and French, A. S. (2002).

Inset shows mean values of Popen at 36 s after the step under normal and acid conditions. 05. On the basis of data from Ho¨ger and French (2002). 1. Mechanotransduction in Spiders 11 Therefore, the single‐channel conductance of the mechanosensitive channels could be 20 pS or more. , 1992). D. Temperature Sensitivity of Mechanosensitive Channels Mechanotransduction has been found to be more thermally sensitive than would be predicted from simple ion channel conductance in a range of vertebrate and invertebrate sensory receptors (reviewed in Ho¨ger and French, 1999b).

Transducing touch in Caenorhabditis elegans. Annu. Rev. Physiol. 65, 429–452. , and Gnatzy, W. (1987). Kþ and Caþþ in the receptor lymph of arthropod cuticular receptors. J. Comp. Physiol. A 161, 329–333. Hamill, O. , and McBride, D. W. (1996). A supramolecular complex underlying touch sensitivity. Trends Neurosci. 19, 258–261. , and French, A. S. (1999a). Estimated single‐channel conductance of mechanically‐ activated channels in a spider mechanoreceptor. Brain Res. 826, 230–235. , and French, A.

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Cascading Activation:Contesting the White House’s Frame After 9 11 by ROBERT M. ENTMAN

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