By Professor Dr. med. Helmut Löffler, Professor Dr. med. Johann Rastetter, Professor Dr. med. Dr. phil. T. Haferlach (auth.)
This sixth variation of the atlas has built-in the 2001 WHO category and made use of figures and outlines to record lately defined sorts of leukemia and lymphoma. The latter contain leukemias of dendritic cells, infrequent lymphomas and chronic polyclonal B lymphocytosis, which takes a different position within the classification.
The quantity covers the entire microscopic equipment in hematology that shape the foundation of analysis in addition to the result of smooth immunologic, cytogenetic and molecular-genetic research. exact emphasis is put on the cytogenetic and molecular-genetic characterization of organic entities that may shape the root for cutting edge therapies.
Normal effects and pathological findings are in comparison, and many of the findings made in the course of remedy are depicted. All in all of the Atlas of medical Hematology represents an entire and worthy reference paintings which can be found in each hematologic and oncologic division in addition to in scientific laboratories for on-line diagnostics and clinical research.
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9 a – d) 44 Congenital Anomalies of Granulocytopoiesis (Fig. 10 a – f) 46 Cells of the Monocyte-Macrophage System (Fig. 13 a – h) 54 Megakaryocytes (Fig. 15 a – e) 60 Osteoblasts and Osteoclasts (Fig. 16 a – f) 63 Lymphocytes and Plasma Cells (Fig. 8 Disturbances of Erythropoiesis 80 Hypochromic Anemias (Fig. 6 Chronic Myeloproliferative Disorders (CMPD) 134 Myeloid Leukemia and Transient Abnormal Myelopoiesis (TAM) of Down Syndrome (DS) 140 Special Variants of Megakaryocyte Proliferation 140 Familial Erythrocytosis (Fig.
The cells at this stage are called metamyelocytes or juvenile forms (Fig. 8 d). A few may be found in the peripheral blood. Metamyelocytes are no longer capable of division. The band neutrophil (Fig. 8 e) is distinguished from the metamyelocyte by its smaller and more coarsely structured nucleus. Its cytoplasm and granules are like those of metamyelocytes. Constrictions begin to appear in the nucleus, but the cell is not classified as a segmented form until the bridge between two nuclear lobes is filiform or less than one-third the width of the adjacent lobes.
6 c) are distinguished by their jagged surface, which usually is deeply clefted. Acanthocytes are seen in a rare hereditary anomaly, A-b-lipoproteinemia. They are also a feature of uremia and hepatic coma, where large numbers of these cells are considered a poor prognostic sign. Acanthocyte formation has also been linked to the use of alcohol and certain drugs. Sickle cells (drepanocytes) (Fig. 6 d). Sickleshaped erythrocytes occasionally form spontaneously, but sickling is consistently induced by oxygen withdrawal in the sickle cell test (see p.
Atlas of Clinical Hematology by Professor Dr. med. Helmut Löffler, Professor Dr. med. Johann Rastetter, Professor Dr. med. Dr. phil. T. Haferlach (auth.)