Antioxidants Against Cancer (Ralph Moss on Cancer) - download pdf or read online

By Ralph W. Moss

ISBN-10: 1881025284

ISBN-13: 9781881025283

Learn the way antioxidants lessen the side-effects of chemotherapy and should even make it more advantageous.

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24]. They prepared a copolymer of glycerol triacrylate (GT)-spermine (SPE), complexed with a tumor-suppressing DNA, and utilized the carrier in successful transfection of gene to the tumor cells which suppressed lung tumorigenesis through apoptosis with no organ toxicity. Tan et al. designed polyethylene glycol (PEG)-phosphatidylethanolamine (PE) nanomicelles and successfully administered orally quercetin drug (a flavonoidbased potential anticancer drug with poor water solubility and less cellular absorbability) to A549 lung cancer cell line in a xenografted model [25].

However, many recent studies report that unfortunately despite the use of stealth strategies, often liposomes are filtered out through the hepatic portal ­system. Hence, stealth liposomes are further functionalized with desirable targeting ligands (antibodies or other moieties directed to specific antigens, receptors, or other ­targets on the pulmonary endothelium) to ensure more accumulation of the NPs in lung cancer cells. Cationic liposomes (composed of charged heads and hydrophobic carbon skeletons) and archeosomes (composed of glycerolipids) are other variations of liposomes.

Rani D, Somasundaram VH, Nair S, Koyakutty M (2012) Advances in cancer nanomedicine. Blum AS, Soto CM, Wilson CD, Cole JD, Kim M, Gnade B, Chatterji A, Ochoa WF, Lin T, Johnson JE, Ratna BR (2004) Cowpea mosaic virus as a scaffold for 3-D patterning of gold nanoparticles. Robertson KL, Soto CM, Archer MJ, Odoemene O, Liu JL (2011) Engineered T4 viral nanoparticles for cellular imaging and flow cytometry. Caruso G, Caffo M, Alafaci C, Raudino G, Cafarella D, Lucerna S, Salpietro FM, Tomasello F (2011) Could nanoparticle systems have a role in the treatment of cerebral gliomas?

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Antioxidants Against Cancer (Ralph Moss on Cancer) by Ralph W. Moss


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